Optimum estimation of the 95 percent effective defibrillation dose

TitleOptimum estimation of the 95 percent effective defibrillation dose
Publication TypeJournal Article
Year of Publication1991
AuthorsMalkin RA, Pilkington TC, Johnson EE, Ideker RE
JournalProceedings of the Annual Conference on Engineering in Medicine and Biology
Volume13
Issuept 2
Start Page758
Pagination758 - 759
Date Published01/1991
Abstract

Optimum Bayesian algorithms were compared with three currently used approaches to estimating the leading edge voltage which successfully defibrillates 95% of the time (ED95). Two different design methods were used for the Bayesian techniques. Five dogs were investigated using the Bayesian algorithms, the up-down technique, the Bourland method, the step-down method, and, for reference, logistic regression. There was excellent agreement between the computer-predicted and measured performances. Both the computer predictions and the animal experimentation confirmed that the Bayesian method is significantly better than the three currently used methods for estimating the ED95.

Short TitleProceedings of the Annual Conference on Engineering in Medicine and Biology