Title | 1-Hydroxypyrene levels in coal-handling workers at a coke oven. |
Publication Type | Journal Article |
Year of Publication | 1996 |
Authors | Malkin R, Kiefer M, Tolos W |
Journal | Journal of occupational and environmental medicine |
Volume | 38 |
Issue | 11 |
Start Page | 1141 |
Pagination | 1141 - 1144 |
Date Published | 11/1996 |
Abstract | An environmental and medical survey was conducted at the coal-handling area of a coke oven, where workers came in contact with coal-tar sludge. The purpose of the study was to determine if skin contact with coal-tar sludge was an important route of exposure to pyrene because workers were observed to have substantial contact with the sludge. Environmental monitoring revealed minimal airborne exposure to pyrene, a byproduct of the coke distillation process; only one personal breathing zone sample detected pyrene, and at least of 0.001 mg/m3. However, the mean preshift urinary 1-hydroxypyrene concentration was 1.00 mumol/mol creatinine (range, 0.16 to 2.96 mumol/mol creatinine) and the mean postshift level was 1.7 mumol/mol creatinine (range, 0.24 to 4.85 mumol/mol creatinine) (P < 0.01). These levels probably reflect absorption as a result of skin exposure. |
DOI | 10.1097/00043764-199611000-00014 |
Short Title | Journal of occupational and environmental medicine |